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Superbug NDM-1

Superbug NDM-1

Why in news  about Superbug NDM-1?

  • In the global spread of multi-drug resistant (MDR) bacteria, scientists have found a “superbug” gene — first detected in New Delhi over a decade back — in one of the last “pristine” places on Earth that is some 12,870 km away.
  • A 70-year-old US woman has died in 2016 because of the superbug NDM-1.

What is super bug ?

A superbug, also called multiresistant, is a bacterium that carries several resistance genes. These are resistant to multiple antibiotics and are able to survive even after exposure to one or more antibiotics

What is Superbug blaNDM-1 in news?

  1. Soil samples taken in Svalbard — a Norwegian archipelago between mainland Norway and the North Pole — have now confirmed the spread of blaNDM-1 (called New Delhi Metallo-beta-lactamase-1) into the High Arctic.
  2. The blaNDM-1 and other ARGs were found in Arctic soils that were likely spread through the faecal matter of birds, other wildlife and human visitors to the area.
  3. This Antibiotic-Resistant Gene (ARG), originally found in Indian clinical settings, conditionally provides multi-drug resistance (MDR) in microorganisms, a/c to the research.
  4. British scientists later found the “superbug” in New Delhi’s public water supply.
  5. Since then, the resistant gene has been found in over 100 countries, including new variants.

What causes them to mutate like that?

  • Like any living organism, bacteria can mutate as they multiply. Also like any living organism, bacteria have a strong evolutionary drive to survive.
  • So, over time, a select few will mutate in particular ways that make them resistant to antibiotics.
  • Then, when antibiotics are introduced, only the bacteria that can resist that treatment can survive to multiply further, proliferating the line of drug-resistant bugs.

Why is Antibiotic Resistance a Big Deal?

  • The discovery of antibiotics less than a century ago was a turning point in public health that has saved countless lives.
  • Although antibiotic resistance develops naturally with normal bacterial mutation, humans are speeding it up by using antibiotics improperly.
  • According to a research, now, 2 million people a year in the US develop antibiotic-resistant infections, and 23,000 of them die of those infections.

Why is the medical community worried?

  • Basically, superbugs are becoming more powerful and widespread than ever. Medical experts are afraid that we’re one step away from deadly, untreatable infections, since the mcr-1 E.coli is resistant to that last-resort antibiotic Colistin.
  • Antibiotic-resistance  passed relatively easily from one bacteria to the next, since it is transmitted by way of loose genetic material that most bacteria have in common.
  • The World Health Organization (WHO) is afraid of a post-antibiotic world, where loads of bacteria are superbugs. Already, infections like tuberculosis, gonorrhea, and pneumonia are becoming harder to treat with typical antibiotics.

What Can We Do?

  • First step would be to limit antibiotic use. If a patient has a virus, for instance, an antibiotic won’t work, so doctors shouldn’t prescribe antibiotics even if the patient insists.
  • And when patients do need antibiotics, it’s important to make sure they take the full course to kill off every last infection-causing germ. Otherwise the strong survive, mutate, and spread.
  • As a society, curbing antibiotic use in healthy animals used in human food production is another important step.

https://www.iasipstnpsc.in/water-pollution-crisis/

https://www.medicalnewstoday.com/articles/197616.php

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