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Agappe Chitra Magna – Shanmugam IAS Academy
Chitra Magna


What’s in news?

The Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST) has commercially launched Agappe Chitra Magna, a magnetic nanoparticle-based RNA extraction kit it has developed along with Agappe Diagnostics Ltd, a Kochi-based invitro diagnostics manufacturing company

Key data’s:

  • Chitra Magna is an innovative RNA extraction kit developed by the SCTIMST, the technology for which had been transferred to Agappe Diagnostics last month.


  • It uses an innovative technology for isolating RNA using magnetic nanoparticles to capture the RNA from the patient sample and is very sensitive.
  • The magnetic nanoparticle beads bind to the viral RNA and, when exposed to a magnetic field, give a highly purified and concentrated RNA.
  • As the sensitivity of the detection method is dependent on getting an adequate quantity of viral RNA, this innovation enhances the chances of identifying positive cases.
  • The kit, which can be used for RNA extraction for RT-LAMP, RT-qPCR, RT-PCR and other isothermal and PCR-based protocols for the detection of SARS-CoV-2, had been validated by the National Institute of Virology, following which the Central Drugs Standard Control Organisation (CDSCO) had given the go ahead for its commercial production.


  • The indigenously developed and manufactured RNA extraction kit would reduce the nation’s dependence on imported kits which are expensive and bring down the cost of COVID-19 testing.

RNA virus:

  • SARS-COV-2, the causative virus of Covid-19 pandemic, is an RNA virus- a long single-stranded polymeric substance present in all living cells that carries the genetic information of the organism necessary for life.
  • One of the critical steps in detecting this virus is by confirming the presence of the RNA of the virus in the sample taken from the throat or nose.

Links to note:

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